An expert view from Ross Maclean, Head of Medical Affairs and Jon Bambalas, SVP, Business Development, Precision Value & Health, on how insights from patient-level health insurance benefits data can serve the pharmaceutical industry – namely, how coverage insights can inform the generation of evidence to demonstrate to payers and providers the value of a specific treatment.
Gilead Sciences, Inc. will present new data at the San Antonio Breast Cancer Symposium (SABCS) 2023 supporting the use of Trodelvy® (sacituzumab govitecan-hziy) in certain metastatic triple-negative breast cancer (mTNBC) and pre-treated HR+/HER2- metastatic breast cancer (mBC) patients. Precision's research with Gilead Sciences on "Understanding Clinical Meaningfulness in Metastatic Breast Cancer Treatment Decision-Making" will be presented during Poster Session 1: Poster # PO1-10-06 on Wednesday, Dec. 6 at 12:00 PM. Co-authored by Meaghan Roach, Rozanne Wilson, Suepattra May-Slater, Melissa Maravic and Emily Freeman.
Precision will be at ISPOR Europe November 12-15, 2023. Don't miss our two Short Courses.
Precision will be at ISPOR Europe November 12-15, 2023. Don't miss our two Workshops.
The presentation by Precision's Marlon Graf of a study with Jim Baumgardner, Iris Brewer, Jacquelyn Chou and Oliver Diaz and their colleagues was named an ISPOR 2023 Research Presentation Award Finalist. The Generalized Risk-Adjusted Cost-Effectiveness framework is a generalization of conventional cost-effectiveness analysis (CEA) and incorporates the effects of diminishing returns to health improvements as severity of illness increases. In the study presented by Marlon, the GRACE framework was applied to assess the comprehensive value of direct-acting antivirals (DAAs) for the treatment of hepatitis C (HCV) compared to peginterferon alfa and ribavirin (PEG/riba), accounting for differential valuations of life years versus quality of life, disease severity, insurance value, and other novel value elements. Please reach out to Marlon to learn more about the GRACE framework.
The presentation by Precision's Dylan Maciel of a study with Shannon Cope, Kevin Towle and Jeroen Jansen and their colleagues was named an ISPOR 2023 Research Presentation Award Finalist. Multi-level network meta-regression (ML-NMR) is a new method to perform network meta-analysis where for a subset of the studies we have individual participant data and for the remaining studies only aggregate level data from publications. In the study presented by Dylan, the feasibility of implementing ML-NMR for survival outcomes was evaluated. We learned a lot from this study that has direct benefit to future PRECISIONheor studies. Please contact Shannon Cope to learn more about ML-NMR (which is a method that is generalization of early work published by our Chief Scientist, Jeroen Jansen, in 2012).
The presentation by Precision's Laura Panattoni of a study with Tom Flottemesch, Natalie Land and Patrick Sullivan and their colleagues at ISPOR 2023 was named the Best General Podium Research Presentation. With this study, Laura and her colleagues aimed to quantify preferences for first line treatment attributes and treatment profiles among physicians who treat patients with aUC in 5 European countries (France, Germany, Italy, Spain, and the UK) with a DCE. Overall survival was the dominant attribute driving physicians’ choice of first line therapy, indicating that future therapies for aUC will need to provide substantial survival benefit to influence prescribing preferences. Reach out to Laura to learn more about this study.
The March Events Calendar is here! Stay up to date with all of the upcoming Precision conferences, on-demand events and recent thought leadership!
New study demonstrates the feasibility of systematically integrating long-term survival estimates obtained from a formal expert elicitation study with empirical clinical trial data through a case study. Learn more about recent work of PRECISIONheor's Shannon Cope (co-primary author), Kevin Towle and Ali Mojebi and their co-authors.
Check out our November Events Calendar, and stay up to date with all of the upcoming and on-demand Precision events and thought leadership!